Abstract:Thiosulfate is considered the most promising alternative reagent for cyanide due to its green, non-toxic, fast gold leaching rate and cheap reagent price. A systematic review of the development state of thiosulfate leaching systems was provided, and the principles of different thiosulfate leaching systems were emphatically described. The problems and countermeasures of conventional thiosulfate leaching systems were discussed, and the potential industrial applications of non-ammonia thiosulfate leaching systems were analyzed. The development and application of the new thiosulfate system will provide theoretical reference and technical support to promote technological progress and healthy sustainable development of gold mining industry in China.