Abstract:The indoor pot experiment was carried out to study the influence of single and double inoculation of Purpureocillium lilacinum（PL）, Paecilomyces sp（PS） and Stenotrophomonas maltophilia（SM） on the tolerance of Rudbeckia hirta (R.hirta) and its combined remediation effect by adding different concentrations of Pb and Cd mixed pollution. The results show that inoculation of microorganisms could effectively alleviate the toxicity of Pb and Cd co-contaminated soil to R.hirta. The biomass of R.hirta rises by 73.1%—207.31% after inoculation of PL and PS, which has the best tolerant ability. The enrichment coefficient and transport coefficient of Pb and Cd of the other five inoculation methods were greater than 1 except for double inoculation of PL and SM, and the enrichment ability of Pb and Cd of the other five inoculation methods is better than that of single inoculation. After inoculation of microorganisms, the content of available Pb and Cd in soil rises by 8.91%—702.22% and 0.13%—23.26% respectively. Under the concentration of Pb 1 500 mg/kg and Cd 1 mg/kg in soil, the combined repair of R.hirta and microorganism has a good effect, which is conducive to the activation of Pb and Cd in soil, and the combination of PL and PS has better inoculation effect.