Abstract:β-branch primary alcohol (A1416) was used as extractant to extract and separate boron from a salt lake brine of high lithium content and mixed chloride and sulfate salts. Effects of brine initial pH value, A1416 concentration, mixing time, phase ratio O/A and temperature on boron extraction were investigated, and the process parameters were optimized. Distribution behaviors of boron and lithium in extraction two-phase system and separation of boron from lithium, magnesium, sodium and potassium were analyzed. When initial pH value of brine is 0.5, organic phase formation is 50% A1416-50% 260# solvent oil, O/A=3/2, mixing time is 5 min and extraction temperature is 20 ℃, the single-stage extraction yield of boron is more than 66% whereas the extraction yields of lithium, magnesium, sodium and potassium is only 0.54%, 0.28%, 0.84% and 0.29%, respectively. The separation coefficients of boron and lithium, magnesium, sodium and potassium is 363, 684, 308 and 679, respectively. A1416 shows good selectivity for boron. The organic phase loaded with boron can be stripped with water to obtain boron-rich solution.