Abstract:Shake flask experiments of low grade gold-copper ores from Zijinshan by bio-heap leaching, media conversion, gold cyaniding extraction were carried out. Copper extraction with different bioleaching duration and influence of copper grade in residue on gold cyaniding were investigated. The results show that 73% of copper is extracted after 12 days bioleaching and copper grade in residue declines to 0.096%. Copper grade exerts significant impact on gold cyanidation. Dosage of sodium cyanide, copper extraction and copper concentration in cyaniding rise with increase of copper grade in bioleaching residues. Copper grade in bioleaching residue should be reduced to 0.1% below in order to reduce impact of copper on cyanide and ensure recovery of copper and gold.